Initiation of the Immune Response by Extracellular Hsp72: Chaperokine Activity of Hsp72
نویسندگان
چکیده
منابع مشابه
Chaperokine function of recombinant Hsp72 produced in insect cells using a baculovirus expression system is retained.
Extracellular heat shock protein 72 (Hsp72; inducible form of the 70-kDa heat shock protein) plays a critical role in innate and adaptive immune responses and has shown promise as an ideal adjuvant for the optimization of antigen-specific anti-tumor vaccines. Recent studies suggest that to correctly elucidate the mechanisms by which Hsp72 exerts its beneficial effects in vitro, great care must ...
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ژورنال
عنوان ژورنال: Current Immunology Reviews
سال: 2006
ISSN: 1573-3955
DOI: 10.2174/157339506778018514